BDBM23408 2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-chromen-4-one::CHEMBL413552::Quercetagetin::Quercetagetin (24)::US11759530, Compound Table1.8
SMILES Oc1ccc(cc1O)-c1oc2cc(O)c(O)c(O)c2c(=O)c1O
InChI Key InChIKey=ZVOLCUVKHLEPEV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 23408
Affinity DataIC50: 1.02E+4nMpH: 6.0 T: 22°CAssay Description:The assay was carried out at room temperature for 10 min with salivary alpha-amylase, starch, and test compounds. The reducing sugar was determined b...More data for this Ligand-Target Pair
Affinity DataIC50: 3.45E+3nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
Affinity DataIC50: 2.62E+3nMAssay Description:The kinase assay was performed using the EMD Millipore KinaseProfiler service assay protocol. Aurora B kinase was supplied by EMD Millipore Corp. The...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Human)
Loma Linda University School of Medicine
Curated by ChEMBL
Loma Linda University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 339nMAssay Description:Inhibition of PIM1 kinaseChecked by AuthorMore data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:IC50 was measured as concentration required to inhibit 50% of HIV-integrase integrationMore data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against HIV-1 integrase by strand transfer methodMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Human)
Loma Linda University School of Medicine
Curated by ChEMBL
Loma Linda University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of Pim1 (unknown origin) assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotomet...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of bovine brain synapsin-1 incubated for 1 hr by ATP-[gamma35S] binding assayMore data for this Ligand-Target Pair
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
University of Strasburg
Curated by ChEMBL
University of Strasburg
Curated by ChEMBL
Affinity DataIC50: 4.86E+4nMAssay Description:Inhibition of human CD38 using 20 uM 1, N6-etheno NAD+ as substrate by continuous fluorimetric methodMore data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibitory concentration to inhibit HIV-1 integrase by 3' -processing methodMore data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:IC50 was measured as concentration required to inhibit 50% of HIV-integrase cleavageMore data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Human)
Loma Linda University School of Medicine
Curated by ChEMBL
Loma Linda University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) expressed in Escherichia coli after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Mouse)
National Clinical Research Center For Geriatrics
Curated by ChEMBL
National Clinical Research Center For Geriatrics
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of JNK1 in mouse JB6 C1 41 cell lysate incubated for 1 hr relative to controlMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Human)
Loma Linda University School of Medicine
Curated by ChEMBL
Loma Linda University School of Medicine
Curated by ChEMBL
TargetSerine/threonine-protein kinase pim-1(Human)
Loma Linda University School of Medicine
Curated by ChEMBL
Loma Linda University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 340nMpH: 7.0 T: 30°CAssay Description:The 96-well flat-bottomed plates were coated with recombinant GST-BAD. After the plates were blocked, the reaction buffer containing test compound an...More data for this Ligand-Target Pair