BDBM50088001 (+/-)-11-[2-(2-methoxyphenyl)acryloyl]-1-phenyl-(1R,8R,9S,13S)-11-azatetracyclo[6.5.2.02,7.09,13]pentadeca-2,4,6-triene-9-carboxylic acid (RPR115135)::CHEMBL50637::RPR-115135

SMILES COc1ccccc1C(=C)C(=O)N1C[C@@H]2[C@](C1)([C@@H]1CC[C@@]2(c2ccccc2)c2ccccc12)C(O)=O

InChI Key InChIKey=UMLXJXCOOBRTMY-XSVIJKGOSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50088001   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50088001((+/-)-11-[2-(2-methoxyphenyl)acryloyl]-1-phenyl-(1...)
Affinity DataKi:  25nMAssay Description:Inhibition of farnesyltransferase by Ras/SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50088001((+/-)-11-[2-(2-methoxyphenyl)acryloyl]-1-phenyl-(1...)
Affinity DataIC50:  50nMAssay Description:Inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed