BDBM50080477 3-[(S)-3-(Naphthalene-2-sulfonylamino)-2-oxo-pyrrolidin-1-ylmethyl]-benzamidine::3-[3-((S)-Naphthalene-2-sulfonylamino)-2-oxo-pyrrolidin-1-ylmethyl]-benzamidine::CHEMBL93796::RPR-118071

SMILES NC(=N)c1cccc(CN2CC[C@H](NS(=O)(=O)c3ccc4ccccc4c3)C2=O)c1

InChI Key InChIKey=NTFWSCPFRKNWEI-FQEVSTJZSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50080477   

TargetCoagulation factor X(Human)
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Curated by ChEMBL
LigandPNGBDBM50080477(3-[(S)-3-(Naphthalene-2-sulfonylamino)-2-oxo-pyrro...)
Affinity DataKi:  80nMAssay Description:Inhibitory activity against Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
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Curated by ChEMBL
LigandPNGBDBM50080477(3-[(S)-3-(Naphthalene-2-sulfonylamino)-2-oxo-pyrro...)
Affinity DataKi:  230nMAssay Description:Binding affinity against serine protease Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
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Curated by ChEMBL
LigandPNGBDBM50080477(3-[(S)-3-(Naphthalene-2-sulfonylamino)-2-oxo-pyrro...)
Affinity DataKi:  230nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
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Curated by ChEMBL
LigandPNGBDBM50080477(3-[(S)-3-(Naphthalene-2-sulfonylamino)-2-oxo-pyrro...)
Affinity DataKi:  230nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bovine)
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Curated by ChEMBL
LigandPNGBDBM50080477(3-[(S)-3-(Naphthalene-2-sulfonylamino)-2-oxo-pyrro...)
Affinity DataKi:  2.90E+3nMAssay Description:Inhibitory activity against bovine pancreatic trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Human)
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Curated by ChEMBL
LigandPNGBDBM50080477(3-[(S)-3-(Naphthalene-2-sulfonylamino)-2-oxo-pyrro...)
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Human)
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Curated by ChEMBL
LigandPNGBDBM50080477(3-[(S)-3-(Naphthalene-2-sulfonylamino)-2-oxo-pyrro...)
Affinity DataKi:  4.70E+3nMAssay Description:Compound was evaluated for the inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Human)
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Curated by ChEMBL
LigandPNGBDBM50080477(3-[(S)-3-(Naphthalene-2-sulfonylamino)-2-oxo-pyrro...)
Affinity DataKi:  7.00E+3nMAssay Description:Compound was evaluated for the inhibition of Activated protein C (aPC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Human)
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Curated by ChEMBL
LigandPNGBDBM50080477(3-[(S)-3-(Naphthalene-2-sulfonylamino)-2-oxo-pyrro...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for the inhibition of Tissue type plasminogen activator (tissue plasminogen activator)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed