BDBM88664 US10189794, Compound I-27::US10618902, Compound I-27::US10774052, Compound I-27::US9695132, I-27
SMILES COc1cc(OC)cc(c1)N1Cc2cnc(Nc3cc(ccc3NC(=O)C=C)-c3cnn(C)c3)nc2N(C)C1=O
InChI Key InChIKey=AJASVIXFAYLXIB-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 88664
Affinity DataIC50: <100nMpH: 7.5Assay Description:Omnia Assay Protocol for Potency Assessment Against FGFR 4 Enzyme. a) [FGFR4-WT]=10 nM, [ATP]=300 uM, [Y10-Sox]=10 uM (ATP KMapp 300 uM): A 10x stock...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:For MDA-MB-453 cells signaling, cells were grown in 96-well poly-D-lysine plates (BD Bioscience, San Jose, Calif.) to 90% confluence, and were then i...More data for this Ligand-Target Pair
Affinity DataIC50: <500nMAssay Description:A 10× stock solution of FGFR4-WT (PR4380C or P3054), (from Invitrogen, Carlsbad, Calif.) corresponding to method a in Table 10, was prepared as descr...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:A 10× stock solution of FGFR4-WT (PR4380C), (from Invitrogen, Carlsbad, Calif.) corresponding to method a in Table 7, was prepared as described below...More data for this Ligand-Target Pair