BDBM50208336 (R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-(3-chlorophenyl)-2-hydroxyethanone::CHEMBL238744::SR-889

SMILES O[C@@H](C(=O)N1CCN(CC1)c1ccc2[nH]ncc2c1)c1cccc(Cl)c1

InChI Key InChIKey=MRGGOQVTDADSFB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50208336   

TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208336((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-(3-chl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208336((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-(3-chl...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed