BDBM50469700 (-)-OR-1259::CHEBI:50567::Levosimendan::OR-1259::Simdax

SMILES [H][C@@]1([#6])[#6]-[#6](=O)-[#7]-[#7]=[#6]1-c1ccc(-[#7]\[#7]=[#6](/C#N)C#N)cc1

InChI Key InChIKey=ZCUQQYPJPNQZIZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50469700   

LigandPNGBDBM50469700(CHEBI:50567 | (-)-OR-1259 | Levosimendan | OR-1259...)
Affinity DataIC50: 8nMAssay Description:Inhibition of phosphodiesterase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2020
Entry Details Article

TargetCytochrome P450 2A2(Rat)
Cytokinetics, Inc.

Curated by ChEMBL
LigandPNGBDBM50469700(CHEBI:50567 | (-)-OR-1259 | Levosimendan | OR-1259...)
Affinity DataKd:  1.00E+5nMAssay Description:Binding affinity to recombinant human Cardiac troponin C (1 to 89 residues) expressed in Escherichia coli assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed