BDBM32168 2,5-bis(chloranyl)-N-[3-(2-hydroxyphenyl)-4-oxidanyl-phenyl]benzenesulfonamide::2,5-dichloro-N-[4-hydroxy-3-(2-hydroxyphenyl)phenyl]benzenesulfonamide::TG2-90-1::cid_16072262

SMILES Oc1ccccc1-c1cc(NS(=O)(=O)c2cc(Cl)ccc2Cl)ccc1O

InChI Key InChIKey=GLGODKFZFFZDDG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 32168   

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM32168(TG2-90-1 | cid_16072262 | 2,5-bis(chloranyl)-N-[3-...)
Affinity DataIC50: 1.94E+4nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32168(TG2-90-1 | cid_16072262 | 2,5-bis(chloranyl)-N-[3-...)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details
PCBioAssay
TargetHeat shock protein HSP 90-alpha(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32168(TG2-90-1 | cid_16072262 | 2,5-bis(chloranyl)-N-[3-...)
Affinity DataIC50: 6.00E+4nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2011
Entry Details
PCBioAssay