BDBM50017103 9,10-Dimethoxy-3-methyl-2-(2,4,6-trimethyl-phenylimino)-2,3,6,7-tetrahydro-pyrimido[6,1-a]isoquinolin-4-one::9,10-Dimethoxy-3-methyl-2-(2,4,6-trimethyl-phenylimino)-2,3,6,7-tetrahydro-pyrimido[6,1-a]isoquinolin-4-one.HCl::CHEMBL285913::Trequinsin
SMILES COc1cc2CCn3c(c\c(=N/c4c(C)cc(C)cc4C)n(C)c3=O)-c2cc1OC
InChI Key InChIKey=MCMSJVMUSBZUCN-YYDJUVGSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50017103
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Centre De Neurochimie Du Cnrs
Curated by ChEMBL
Centre De Neurochimie Du Cnrs
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of cGMP-PDE phosphodiesterase from bovine aorta using 1 uM cGMPMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 5(Human)
The Netherlands Cancer Institute
Curated by ChEMBL
The Netherlands Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP5-expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
The Netherlands Cancer Institute
Curated by ChEMBL
The Netherlands Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP4-expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Centre De Neurochimie Du Cnrs
Curated by ChEMBL
Centre De Neurochimie Du Cnrs
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cAMP for cAMP-PDE.More data for this Ligand-Target Pair