BDBM50395584 CHEMBL2165131::UNC10099972::US9156822, 30
SMILES Clc1cccc(N2CCN(Cc3cccc(Oc4ccc5CCC(=O)Nc5c4)c3)CC2)c1Cl
InChI Key InChIKey=PULGLQOWTRCVQB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50395584
Affinity DataEC50: 58nMpH: 7.4Assay Description:Recruitment of β-arrestin to agonist-stimulated D2 receptors was performed using a previously described Tango-type assay (Barnea et al., Proc. N...More data for this Ligand-Target Pair
Affinity DataKi: 113nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 113nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
Affinity DataEC50: 316nMAssay Description:Partial agonist activity at D2L receptor in human HTLA cells assessed as beta arrestin recruitment at 6 uM after 18 hrs by luminescence assayMore data for this Ligand-Target Pair