BDBM50361014 CHEMBL260549::VUF-10214

SMILES CN1CCN(CC1)c1nc2cc(Cl)c(Cl)cc2[nH]c1=O

InChI Key InChIKey=MFJVHWQDKIEBCM-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50361014   

TargetHistamine H4 receptor(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50361014(VUF-10214 | CHEMBL260549)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50361014(VUF-10214 | CHEMBL260549)
Affinity DataKi:  5.62nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50361014(VUF-10214 | CHEMBL260549)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50361014(VUF-10214 | CHEMBL260549)
Affinity DataEC50:  25nMAssay Description:Agonist activity at histamine H4 receptor (unknown origin) expressed in human U2OS cells increase in beta-arrestin2 recruitment after 2 hrs by lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed