BDBM50409817 CHEMBL78498::VUF-5681

SMILES C(CC1CCNCC1)Cc1cnc[nH]1

InChI Key InChIKey=YPGRNKJNOSUCLY-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50409817   

TargetHistamine H3 receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50409817(VUF-5681 | CHEMBL78498)
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]-NR-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cells by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50409817(VUF-5681 | CHEMBL78498)
Affinity DataKi:  4.5nMAssay Description:Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50409817(VUF-5681 | CHEMBL78498)
Affinity DataEC50:  8.30nMAssay Description:Inhibitory activity determined by the inhibition of cAMP- stimulated beta-galactosidase transcription in SK-N-MC cells expressing the human Histamine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50409817(VUF-5681 | CHEMBL78498)
Affinity DataKi:  616nMAssay Description:Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50409817(VUF-5681 | CHEMBL78498)
Affinity DataEC50: <1.00E+4nMAssay Description:Inhibitory activity determined by the inhibition of cAMP- stimulated beta-galactosidase transcription in SK-N-MC cells expressing the human Histamine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed