BDBM50006795 2-(Naphthalen-1-yloxymethyl)-quinoline::CHEMBL84750::WY-47288

SMILES C(Oc1cccc2ccccc12)c1ccc2ccccc2n1

InChI Key InChIKey=NZLDBNPKNBCGEN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50006795   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006795(2-(Naphthalen-1-yloxymethyl)-quinoline | CHEMBL847...)
Affinity DataIC50:  400nMAssay Description:The compound was tested for inhibitory activity against 5-lipoxygenase in rat polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006795(2-(Naphthalen-1-yloxymethyl)-quinoline | CHEMBL847...)
Affinity DataIC50:  6.30E+3nMAssay Description:The compound was tested for inhibitory activity against cyclooxygenase in rat polymorphonuclear leukocytes[PMNS]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(Mus musculus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006795(2-(Naphthalen-1-yloxymethyl)-quinoline | CHEMBL847...)
Affinity DataIC50:  4.40E+4nMAssay Description:The compound was tested for inhibitory activity against 5-lipoxygenase translocation inhibitor in RBL-2H3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006795(2-(Naphthalen-1-yloxymethyl)-quinoline | CHEMBL847...)
Affinity DataIC50:  200nMAssay Description:The compound was tested for inhibitory activity against 5-lipoxygenase in mouse macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed