BDBM50153835 1-(3-dimethylaminophenylcarboxamido)-3-(4-hydroxyphenylcarboxamido)-4-methylbenzene::3-(dimethylamino)-N-(3-(4-hydroxybenzamido)-4-methylphenyl)benzamide::CHEMBL186526::N-[5-(3-dimethylaminobenzamido)-2-methylphenyl]-4-hydroxybenzamide::ZM-336372
SMILES CN(C)c1cccc(c1)C(=O)Nc1ccc(C)c(NC(=O)c2ccc(O)cc2)c1
InChI Key InChIKey=PYEFPDQFAZNXLI-UHFFFAOYSA-N
Data 13 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50153835
Affinity DataIC50: 180nMAssay Description:Concentration required to inhibit human mitogen activated protein kinase p38 activity More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of protein kinase c-rafMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of c-Raf kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of c-Raf in the presence of 100uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of B-Raf in the presence of 100uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of Lck in the presence of 50uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of 17-AAG-induced HSF1 pathway in human SKOV3 cells assessed as reduction in HSP72 induction preincubated for 1 hr followed by 17-AAG addi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of SAPK2a/p38-alphaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of SAPK2b/p38betaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of cRAF1Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 17-AAG-induced HSF1 pathway in human SKOV3 cells assessed as reduction in HSP72 induction preincubated for 1 hr followed by 17-AAG addi...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
University of Dundee
Curated by ChEMBL
University of Dundee
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of RIP2 in the presence of 100uM ATPMore data for this Ligand-Target Pair