BDBM18135 ({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}methyl)phosphonic acid::AMPPCP::ATP,Beta Gamma-me::CHEMBL133463::adenylylmethylenediphosphonate
SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)CP(O)(O)=O)[C@@H](O)[C@H]1O
InChI Key InChIKey=UFZTZBNSLXELAL-IOSLPCCCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 18135
Affinity DataKi: 800nM ΔG°: -8.31kcal/mole IC50: 1.00E+4nMpH: 7.5 T: 25°CAssay Description:Aminoacyl-tRNA synthetase assays were measuring the incorporation of [14C] amino acid into tRNA.More data for this Ligand-Target Pair
Affinity DataKi: 3.00E+5nMAssay Description:Tested for its binding affinity against glycerol kinase (ATP competitive inhibition)More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 1 hit for monomerid = 18135
ITC DataΔG°: -8.67kcal/mole −TΔS°: 7.57kcal/mole ΔH°: -16.9kcal/mole logk: 2.17E+6
pH: 7.2 T: 24.85°C
pH: 7.2 T: 24.85°C