BDBM50177114 CHEMBL1203938::CHEMBL374810::cid_1474879

SMILES COc1cc2ncnc(NCc3ccc(F)cc3)c2cc1OC

InChI Key InChIKey=LASSDHMCHFNZJI-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50177114   

TargetEpidermal growth factor receptor(Human)
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50177114BDBM50177114(CHEMBL374810 | CHEMBL1203938 | cid_1474879)
Affinity DataIC50: 10.9nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50177114BDBM50177114(CHEMBL374810 | CHEMBL1203938 | cid_1474879)
Affinity DataIC50: 47.7nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed