BDBM50247466 CHEMBL462629::cid_5600879::ethyl 2-cyano-2-(quinoxalin-2(1H)-ylidene)acetate

SMILES CCOC(=O)C(C#N)c1cnc2ccccc2n1

InChI Key InChIKey=KKQBQZXMEPUMLX-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50247466   

TargetCollagenase 3(Human)
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50247466(cid_5600879 | CHEMBL462629 | ethyl 2-cyano-2-(quin...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human recombinant MMP13 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50247466(cid_5600879 | CHEMBL462629 | ethyl 2-cyano-2-(quin...)
Affinity DataIC50: 1.03E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2011
Entry Details
PCBioAssay
TargetImportin subunit alpha-1(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50247466(cid_5600879 | CHEMBL462629 | ethyl 2-cyano-2-(quin...)
Affinity DataEC50: >2.60E+5nMAssay Description:Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2011
Entry Details
PCBioAssay