BDBM50066370 5-Methyl-pyridine-2-sulfonic acid {6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-2-[2-(2H-tetrazol-5-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide::CHEMBL109648::clazosentan
SMILES COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCCO)-c1ccnc(c1)-c1nnn[nH]1
InChI Key InChIKey=LFWCJABOXHSRGC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50066370
Affinity DataKi: 0.130nMAssay Description:Tested for binding affinity for human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from chinese hamster ovary cells(CHO)More data for this Ligand-Target Pair
Affinity DataKi: 175nMAssay Description:Tested for binding affinity for human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from chinese hamster ovary cells(CHO)More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Displacement of 125I-ET1 from ETA receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 175nMAssay Description:Displacement of radioligand from ETB receptor in human placenta cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Displacement of 125I-ET1 from ETA receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 175nMAssay Description:Displacement of radioligand from ETB receptor in human placenta cell membranesMore data for this Ligand-Target Pair