BDBM50164644 2',3'-Dideoxyadenosine Triphosphate (Ddatp)::2',3'-dideoxyadenosine triphosphate::ATP,2',3'-dideoxy::CHEMBL1383::[[[5-(6-amino-9H-purin-9-yl)tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphonic acid::ddA-TP::ddATP
SMILES Nc1ncnc2n(cnc12)[C@H]1CC[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O1
InChI Key InChIKey=OAKPWEUQDVLTCN-NKWVEPMBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50164644
Affinity DataKi: 20nMAssay Description:Inhibitory constant against HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Mcgill University
Curated by ChEMBL
Mcgill University
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Inhibition of HIV1 reverse transcriptase M41L/D67N/L210W/T215Y mutant by steady state nucleotide incorporation assayMore data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Inhibition of HIV1 reverse transcriptase by steady state nucleotide incorporation assayMore data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptase (RT M184V)More data for this Ligand-Target Pair
Affinity DataKi: 510nMAssay Description:Inhibitory activity against HIV-1 Reverse transcriptase wild-type (RT wt)More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Inhibitory activity against HIV-1 reverse transcriptase (RT M184I)More data for this Ligand-Target Pair
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human DNA polymerase beta using 5-end radiolabeled 24nt to 48nt DNA as primer template after 5 mins in presence of dCTP/dGTP/dTTP/dATP ...More data for this Ligand-Target Pair
Affinity DataKd: 5.30E+3nMAssay Description:Binding affinity to HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human DNA polymerase beta using 5-end radiolabeled 24nt to 48nt DNA as primer template after 5 mins in presence of dCTP/dGTP/dTTP/dATP ...More data for this Ligand-Target Pair