BDBM50307794 2-(4-isobutylphenyl)-N-(3-methylpyridin-2-yl)propanamide::CHEMBL596757::ibu-am5 (2)
SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)Nc1ncccc1C
InChI Key InChIKey=ZBKGVYYUEQPQPO-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50307794
Affinity DataIC50: 520nMpH: 7.0 T: 2°CAssay Description:Frozen (−80°C) brains (minus cerebella) from adult Wistar or Sprague-Dawley rats were thawed and homogenized in 20 mM HEPES, 1 mM MgCl2, pH 7....More data for this Ligand-Target Pair
Affinity DataIC50: 650nMpH: 7.0 T: 2°CAssay Description:Frozen (−80°C) brains (minus cerebella) from adult Wistar or Sprague-Dawley rats were thawed and homogenized in 20 mM HEPES, 1 mM MgCl2, pH 7....More data for this Ligand-Target Pair
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of sheep COX2 pre-incubated for 5 mins before anandamide acid substrate addition by peroxidase activity detection based oxygen electrode a...More data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of FAAH in rat brain homogenates pre-incubated for 10 mins before addition of [3H]anandamide and [3H]AEA substrates for 30 mins by liquid ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of sheep COX1 pre-incubated for 5 mins before arachidonic acid substrate addition in presence of DMSO by peroxidase activity detection bas...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of FAAH in Sprague-Dawley rat cerebellum membranes pre-incubated for 10 mins before addition of [3H]AEA substrate in presence of ethyl alc...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibition of ovine COX1 pre-incubated for 10 mins before arachidonic acid substrate addition by enzyme immunoassayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 2.40E+5nMAssay Description:Inhibition of sheep COX1 pre-incubated for 5 mins before arachidonic acid substrate addition in presence of ethanol by peroxidase activity detection ...More data for this Ligand-Target Pair