BDBM50252521 CHEMBL492828::isoxanthohumol

SMILES [#6]-[#8]-c1cc(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c2-[#8]-[#6](-[#6]-[#6](=O)-c12)-c1ccc(-[#8])cc1

InChI Key InChIKey=YKGCBLWILMDSAV-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50252521   

TargetBeta-secretase 1(Homo sapiens (Human))
Gyeongsang National University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50252521(CHEMBL492828 | isoxanthohumol)
Affinity DataIC50:  2.77E+4nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50252521(CHEMBL492828 | isoxanthohumol)
Affinity DataIC50:  4.53E+4nMAssay Description:Inhibition of human PKC alpha assessed as inhibition of [33P] incorporation into substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Hallertauer Hopfenveredelung

Curated by ChEMBL
LigandPNGBDBM50252521(CHEMBL492828 | isoxanthohumol)
Affinity DataEC50:  1.40E+3nMAssay Description:Estrogenic activity at estrogen receptor alpha in human Ishikawa cells assessed as induction of alkaline phosphatase activity using p-Nitrophenol pho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50252521(CHEMBL492828 | isoxanthohumol)
Affinity DataIC50:  3.16E+4nMAssay Description:Inhibition of human PKC theta assessed as inhibition of [33P] incorporation into substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50252521(CHEMBL492828 | isoxanthohumol)
Affinity DataIC50:  5.87E+4nMAssay Description:Inhibition of human PDK1 assessed as inhibition of [33P] incorporation into substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed