BDBM101200 US10189794, Compound I-118::US10774052, Compound I-118::US9695132, I-118
SMILES CCC(=O)N[C@H]1CCCC[C@H]1Nc1ncc2CN(C(=O)N(Cc3cscn3)c2n1)c1c(Cl)c(OC)cc(OC)c1Cl
InChI Key InChIKey=KFTLJNCUVVKQSR-ZWKOTPCHSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 101200
Affinity DataIC50: >1.00E+3nMpH: 7.5Assay Description:Omnia Assay Protocol for Potency Assessment Against FGFR 4 Enzyme. a) [FGFR4-WT]=10 nM, [ATP]=300 uM, [Y10-Sox]=10 uM (ATP KMapp 300 uM): A 10x stock...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:For MDA-MB-453 cells signaling, cells were grown in 96-well poly-D-lysine plates (BD Bioscience, San Jose, Calif.) to 90% confluence, and were then i...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:A 10× stock solution of FGFR4-WT (PR4380C), (from Invitrogen, Carlsbad, Calif.) corresponding to method a in Table 7, was prepared as described below...More data for this Ligand-Target Pair