BDBM101829 US10696661, Compound 74::US9695160, 42::US9796707, Compound 42

SMILES FC(F)(F)c1ccc(N2CCN(Cc3c[nH]c4ccccc34)CC2)c(NC(=O)c2ccc(o2)-c2ccncc2)c1

InChI Key InChIKey=PXTGGKHRMSAKSB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 101829   

TargetSRSF protein kinase 1(Homo sapiens (Human))
The University of Nottingham

US Patent
LigandPNGBDBM101829(US10696661, Compound 74 | US9695160, 42 | US979670...)
Affinity DataIC50:  164nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
The University of Nottingham

US Patent
LigandPNGBDBM101829(US10696661, Compound 74 | US9695160, 42 | US979670...)
Affinity DataIC50:  164nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
The University of Nottingham

US Patent
LigandPNGBDBM101829(US10696661, Compound 74 | US9695160, 42 | US979670...)
Affinity DataIC50:  164nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
In DepthDetails US Patent