BDBM101888 CHEMBL1234485::US8530490, 158
SMILES CC(C)(CCCOCn1ccc(=O)[nH]c1=O)NS(=O)(=O)c1ccccc1
InChI Key InChIKey=RMYLCQFHDYJCJN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 101888
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
US Patent
Taiho Pharmaceutical
US Patent
Affinity DataIC50: 9.48E+3nMAssay Description:The inhibitory activity of the compound against human dUTPase was determined by measuring the production of [5-3H]deoxyuridine monophosphate from [5-...More data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
US Patent
Taiho Pharmaceutical
US Patent
Affinity DataEC50: 5.10E+3nMAssay Description:Inhibition of human dUTPase-mediated cell proliferation in HeLa S3 cells assessed as compound concentration required to reduce 50% of 1 uM of FdUrd T...More data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
US Patent
Taiho Pharmaceutical
US Patent
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
US Patent
Taiho Pharmaceutical
US Patent
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair