BDBM105400 US8575203, II-16

SMILES Fc1ccc(Cn2cncc(C(=O)NCC#Cc3ccc4ncnc(NCC(=O)c5ccccc5)c4c3)c2=O)cc1F

InChI Key InChIKey=QZFDAGYQNSGZOO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 105400   

Target3-phosphoinositide-dependent protein kinase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM105400(US8575203, II-16)
Affinity DataIC50: 218nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
Go to US Patent