BDBM105412 US8575203, II-28

SMILES CNCCCN(C)c1ncnc2ccc(cc12)C#CCNC(=O)c1cccn(Cc2ccc(F)c(F)c2)c1=O

InChI Key InChIKey=LNWZJVSUDLKXEQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 105412   

Target3-phosphoinositide-dependent protein kinase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM105412(US8575203, II-28)
Affinity DataIC50: 110nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
US Patent