BDBM10598 (2S)-2-methyl-5,7-dioxatricyclo[6.4.0.0^{2,6}]dodeca-1(12),8,10-trien-11-yl N-ethylcarbamate::Tetrahydrofurobenzofuran Carbamate 8a

SMILES CCNC(=O)Oc1ccc2OC3OCC[C@@]3(C)c2c1

InChI Key InChIKey=ZEZHVLKHFYAVTB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 10598   

TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10598((2S)-2-methyl-5,7-dioxatricyclo[6.4.0.0^{2,6}]dode...)
Affinity DataIC50: 3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM10598((2S)-2-methyl-5,7-dioxatricyclo[6.4.0.0^{2,6}]dode...)
Affinity DataIC50: 6nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10598((2S)-2-methyl-5,7-dioxatricyclo[6.4.0.0^{2,6}]dode...)
Affinity DataIC50: 6nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM10598((2S)-2-methyl-5,7-dioxatricyclo[6.4.0.0^{2,6}]dode...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2006
Entry Details Article
PubMed