BDBM10607 (-)-(5R)-5-Methyl-4,5-dihydro-2,5-methano-1,3-benzodioxepin-7-yl N-(p-Isopropylphenyl)carbamate::(1R)-1-methyl-8,10-dioxatricyclo[7.2.1.0^{2,7}]dodeca-2,4,6-trien-4-yl N-[4-(propan-2-yl)phenyl]carbamate::Benzodioxepine Carbamate 13b

SMILES CC(C)c1ccc(NC(=O)Oc2ccc3OC4C[C@@](C)(CO4)c3c2)cc1

InChI Key InChIKey=KOFCNZPCQOBXHD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10607   

TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10607((1R)-1-methyl-8,10-dioxatricyclo[7.2.1.0^{2,7}]dod...)
Affinity DataIC50: 54nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10607((1R)-1-methyl-8,10-dioxatricyclo[7.2.1.0^{2,7}]dod...)
Affinity DataIC50: 3.43E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2006
Entry Details Article
PubMed