BDBM10617 (3aS)-3a,8-dimethyl-2H,3H,3aH,8H,8aH-furo[2,3-b]indol-5-yl N-(2-methylphenyl)carbamate::CHEMBL362049::Physovenine Carbamate 22a

SMILES CN1C2OCC[C@@]2(C)c2cc(OC(=O)Nc3ccccc3C)ccc12

InChI Key InChIKey=AGOPIOMWLMAZHS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 10617   

TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10617(CHEMBL362049 | (3aS)-3a,8-dimethyl-2H,3H,3aH,8H,8a...)
Affinity DataIC50: 13nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10617(CHEMBL362049 | (3aS)-3a,8-dimethyl-2H,3H,3aH,8H,8a...)
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10617(CHEMBL362049 | (3aS)-3a,8-dimethyl-2H,3H,3aH,8H,8a...)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10617(CHEMBL362049 | (3aS)-3a,8-dimethyl-2H,3H,3aH,8H,8a...)
Affinity DataIC50: 1.56E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2006
Entry Details Article
PubMed