BDBM10621 US8846719, 341

SMILES Cc1onc(c1COc1ccc(cn1)C(=O)N[C@@H]1CCC[C@@H]1O)-c1ccc(F)cc1

InChI Key InChIKey=HHYQTPAPYWKDNN-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10621   

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Roche Palo Alto

US Patent
LigandPNGBDBM10621(US8846719, 341)
Affinity DataKi:  29.2nM ΔG°:  -9.55kcal/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent