BDBM10624 1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-one dibromide::4-(5-{4-[dimethyl(prop-2-en-1-yl)aminiumyl]phenyl}-3-oxopentyl)-N,N-dimethyl-N-(prop-2-en-1-yl)anilinium dibromide::BW284c51::CHEMBL140020::CHEMBL464538

SMILES C[N+](C)(CC=C)c1ccc(CCC(=O)CCc2ccc(cc2)[N+](C)(C)CC=C)cc1

InChI Key InChIKey=ZAEXMNKDGJNLTA-UHFFFAOYSA-N

Data  10 KI  16 IC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 10624   

TargetAcetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataKi:  10nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataKi:  10nMAssay Description:Dissociation constant for enzyme-inhibitor complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataKi:  10nMAssay Description:Inhibition of human erythrocytes recombinant AChE assessed as dissociation constant for enzyme-inhibitor complexMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataKi:  10nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataKi:  50nMAssay Description:Dissociation constant for enzyme-inhibitor-substrate complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataKi:  50nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataKi:  50nMAssay Description:Inhibition of human erythrocytes recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complexMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataKi:  50nMAssay Description:Non competitive inhibition of human recombinant AChE using ATChCl as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Bos taurus (bovine))
Universit£

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataKi:  57nMAssay Description:Inhibition of bovine AChEMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataKi:  800nMAssay Description:Inhibition of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataIC50:  3.54E+5nMAssay Description:Inhibition of human plasmatic BChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against AcetylcholinesteraseMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataIC50:  8nMAssay Description:Inhibition acetylcholinesterase (AChE) enzyme.More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataIC50:  3.54E+5nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataIC50:  3.54E+5nMAssay Description:Inhibition of human plasmatic BChE by modified Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human erythrocyte recombinant AChE by modified Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataIC50:  10nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataIC50:  63nMAssay Description:Inhibition of electric eel AchE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataIC50:  2.55E+5nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Universit£

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataIC50:  8nMAssay Description:Inhibition of bovine AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataIC50:  3.54E+5nMAssay Description:Inhibition of human plasmatic BChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataIC50:  18nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataIC50:  4.80E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed