BDBM110053 US8609678, 4-(1-(4-fluorophenyl)-1-hydroxyethyl)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide [106]::US8609678, 4-(1-(4-fluorophenyl)-1-hydroxyethyl)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide [116]

SMILES CC(O)(c1ccc(F)cc1)c1ccc(cc1)C(=O)NCCCCCCC(=O)NO

InChI Key InChIKey=PQSDQJDMOKAKSB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 110053   

TargetHistone deacetylase 6(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM110053(US8609678, 4-(1-(4-fluorophenyl)-1-hydroxyethyl)-N...)
Affinity DataIC50: 3nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM110053(US8609678, 4-(1-(4-fluorophenyl)-1-hydroxyethyl)-N...)
Affinity DataIC50: 3nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM110053(US8609678, 4-(1-(4-fluorophenyl)-1-hydroxyethyl)-N...)
Affinity DataIC50: 42nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM110053(US8609678, 4-(1-(4-fluorophenyl)-1-hydroxyethyl)-N...)
Affinity DataIC50: 42nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
US Patent