BDBM11071 2-cyanopyrrolidine 24b::methyl 4-[({[(2R,5S)-5-{[(2S)-2-cyanopyrrolidin-1-yl]carbonyl}pyrrolidin-2-yl]methyl}carbamoyl)amino]benzoate

SMILES COC(=O)c1ccc(NC(=O)NC[C@H]2CC[C@H](N2)C(=O)N2CCC[C@H]2C#N)cc1

InChI Key InChIKey=KSXRUYFDGXPBBO-IKGGRYGDSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11071   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM11071(2-cyanopyrrolidine 24b | methyl 4-[({[(2R,5S)-5-{[...)
Affinity DataKi:  6.70nM ΔG°:  -11.0kcal/molepH: 7.5 T: 2°CAssay Description:The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed