BDBM112691 US8629158, 16::US8629158, 4

SMILES Cn1c2CC3CCC(N3)c2c2ccc(cc12)-n1ccc(cc1=O)-c1ccc(cn1)C(F)(F)F

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 112691   

TargetMelanin-concentrating hormone receptor 1(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM112691(US8629158, 16 | US8629158, 4)
Affinity DataKi:  14nM ΔG°:  -10.7kcal/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent

TargetMelanin-concentrating hormone receptor 1(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM112691(US8629158, 16 | US8629158, 4)
Affinity DataKi:  16.1nM ΔG°:  -10.6kcal/molepH: 7.4 T: 2°CAssay Description:Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2014
Entry Details
US Patent