BDBM113091 US8633206, 9

SMILES CN([C@H]1CC[C@H](CS(=O)(=O)N2CCC(O)CC2)CC1)c1ncnc2[nH]ccc12

InChI Key InChIKey=QUUQHDKVPKLLLY-SHTZXODSSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 113091   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM113091(US8633206, 9)
Affinity DataIC50:  342nMpH: 7.4Assay Description:A peptide mobility shift assay was used to quantify the phosphorylation of the JAKtide (JAK2 and JAK3) or the IRS-1 peptide (JAK1 and Tyk2). Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM113091(US8633206, 9)
Affinity DataIC50:  9.18nMpH: 7.4Assay Description:A peptide mobility shift assay was used to quantify the phosphorylation of the JAKtide (JAK2 and JAK3) or the IRS-1 peptide (JAK1 and Tyk2). Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM113091(US8633206, 9)
Affinity DataIC50:  34.2nMpH: 7.4Assay Description:A peptide mobility shift assay was used to quantify the phosphorylation of the JAKtide (JAK2 and JAK3) or the IRS-1 peptide (JAK1 and Tyk2). Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent