BDBM113415 US8633204, 102::US8633204, 229

SMILES Cc1nc(N)nc2n(C3CCCC3)c(=O)c(cc12)-c1cnc(N)cn1

InChI Key InChIKey=GPQOCDDGURBEKR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 113415   

LigandChemical structure of BindingDB Monomer ID 113415BDBM113415(US8633204, 229 | US8633204, 102)
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 113415BDBM113415(US8633204, 229 | US8633204, 102)
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent