BDBM116333 US8637532, 14::US8637532, 248::US8637532, 326

SMILES CNCC(Nc1ncnc2c(cccc12)C(N)=O)c1ccccc1

InChI Key InChIKey=KFUGVCOVSKGHMS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 116333   

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 116333BDBM116333(US8637532, 326 | US8637532, 248 | US8637532, 14)
Affinity DataIC50: 3.80nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 116333BDBM116333(US8637532, 326 | US8637532, 248 | US8637532, 14)
Affinity DataIC50: 3.80nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 116333BDBM116333(US8637532, 326 | US8637532, 248 | US8637532, 14)
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase A(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 116333BDBM116333(US8637532, 326 | US8637532, 248 | US8637532, 14)
Affinity DataIC50: 450nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase A(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 116333BDBM116333(US8637532, 326 | US8637532, 248 | US8637532, 14)
Affinity DataIC50: 450nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase A(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 116333BDBM116333(US8637532, 326 | US8637532, 248 | US8637532, 14)
Affinity DataIC50: 2.50E+3nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent