BDBM116901 US8637532, 627

SMILES NC(=O)c1cccc2c(NCc3cccc(c3)-n3c(=O)[nH]c4ccccc4c3=O)ncnc12

InChI Key InChIKey=XMRRAMCZSADQLM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 116901   

TargetAurora kinase A(Human)
Merck Patent

US Patent
LigandPNGBDBM116901(US8637532, 627)
Affinity DataIC50: 29nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM116901(US8637532, 627)
Affinity DataIC50: 140nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent