BDBM116910 US8637532, 636

SMILES CCN(CC)CCOC1C=CC(C(O)Nc2cccc(CNc3ncnc4c(C(N)=O)cccc34)c2)=CC1

InChI Key InChIKey=HZUXHEBYLGLOGZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 116910   

TargetAurora kinase A(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 116910BDBM116910(US8637532, 636)
Affinity DataIC50: 9.80nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 116910BDBM116910(US8637532, 636)
Affinity DataIC50: 59nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent