BDBM117661 US8653087, III-341

SMILES Cc1ccc(cc1Nc1ncnc2cnc(nc12)N1CCNCC1)C(=O)Nc1cccc(c1)C(C)(C)C

InChI Key InChIKey=NLQUZIAGMWMADE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 117661   

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117661(US8653087, III-341)
Affinity DataIC50: 1nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent