BDBM117810 US8653087, III-490

SMILES Cc1ccc(cc1Nc1ncnc2cnc(nc12)N1CCC(CC1)N1CCCC1)C(=O)Nc1cc(on1)C(C)(C)C

InChI Key InChIKey=RVCMLESCMBIMND-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 117810   

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM117810(US8653087, III-490)
Affinity DataIC50: 2nMpH: 7.5Assay Description:The final concentration of DMSO is 5%. 10 μL of the B-Raf (V600E)-kinase solution are pipetted in (containing 0.5 ng B-Raf (V600E)-kinase in 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent