BDBM119720 US8680132, C086::US9079913, C086

SMILES CC(C)(C)C[C@H]1N[C@@H](C(=O)N[C@H]2C[C@@](C)(O)C2)[C@H](c2cccc(F)c2F)[C@@]12C(=O)Nc1c2ccc(Cl)c1F

InChI Key InChIKey=SXAAXEGAEPWLGA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 119720   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 119720BDBM119720(US8680132, C086 | US9079913, C086)
Affinity DataIC50: 402nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 119720BDBM119720(US8680132, C086 | US9079913, C086)
Affinity DataIC50: 3.00E+3nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details
US Patent