BDBM119947 US8697911, 100

SMILES CN(C)[C@H]1CCc2nc(NC(=O)c3cccc(CNC(=O)c4cn5cc(ccc5n4)C#N)c3)sc2C1

InChI Key InChIKey=SMAHIGCEYQYKLG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 119947   

TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM119947(US8697911, 100)
Affinity DataIC50: 1.70nMpH: 7.5 T: 2°CAssay Description:The activity of ROCKII (1-543) kinase is measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-luc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2014
Entry Details
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TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM119947(US8697911, 100)
Affinity DataIC50: 2.60nMpH: 7.2Assay Description:This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2014
Entry Details
Go to US Patent