BDBM120395 US8703771, 13::US8703771, 14::US8703771, 8
SMILES CN1CCN(CC1)C1CCc2cc(ccc12)C(=O)Nc1ccc(C)c(Nc2nccc(n2)-c2cncnc2)c1
InChI Key InChIKey=IQOAIXAFDYRGNK-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 120395
Affinity DataIC50: 5.30nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
Affinity DataIC50: 266nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Harbin Gloria Pharmaceuticals
US Patent
Harbin Gloria Pharmaceuticals
US Patent
Affinity DataIC50: 32nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Harbin Gloria Pharmaceuticals
US Patent
Harbin Gloria Pharmaceuticals
US Patent
Affinity DataIC50: 65nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Harbin Gloria Pharmaceuticals
US Patent
Harbin Gloria Pharmaceuticals
US Patent
Affinity DataIC50: 2.26E+3nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Harbin Gloria Pharmaceuticals
US Patent
Harbin Gloria Pharmaceuticals
US Patent
Affinity DataIC50: 22nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Harbin Gloria Pharmaceuticals
US Patent
Harbin Gloria Pharmaceuticals
US Patent
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Harbin Gloria Pharmaceuticals
US Patent
Harbin Gloria Pharmaceuticals
US Patent
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair