BDBM122829 US8735386, II-13::US8735386, II-7

SMILES COc1cc(ccc1Nc1ncc2CCc3nn(C)c(C(C)c4ccccc4)c3-c2n1)C(O)=O

InChI Key InChIKey=TZYBLNLDVCJCKQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 122829   

TargetInsulin-like growth factor 1 receptor(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM122829(US8735386, II-13 | US8735386, II-7)
Affinity DataIC50: 246nMpH: 7.4Assay Description:The kinase activity is measured by DELFIA assay (dissociation-enhanced lanthanide fluorescence immunoassay, Perkin Elmer). The cytoplasmic kinase dom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
Go to US Patent

TargetInsulin-like growth factor 1 receptor(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM122829(US8735386, II-13 | US8735386, II-7)
Affinity DataIC50: 246nMpH: 7.4Assay Description:The kinase activity is measured by DELFIA assay (dissociation-enhanced lanthanide fluorescence immunoassay, Perkin Elmer). The cytoplasmic kinase dom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
Go to US Patent