BDBM122835 US8735386, II-14

SMILES Cn1nc2CCc3cnc(Nc4cccc5cc(sc45)C(O)=O)nc3-c2c1Cc1ccccc1

InChI Key InChIKey=NHOPISLCMLRKFW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 122835   

TargetInsulin-like growth factor 1 receptor(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM122835(US8735386, II-14)
Affinity DataIC50: 94nMpH: 7.4Assay Description:The kinase activity is measured by DELFIA assay (dissociation-enhanced lanthanide fluorescence immunoassay, Perkin Elmer). The cytoplasmic kinase dom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent