BDBM122837 US8735386, II-16

SMILES Cc1ccccc1-c1c-2c(CCc3cnc(Nc4ccc(cc4Cl)C(O)=O)nc-23)nn1C

InChI Key InChIKey=XWCMCIDDLJSDBY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 122837   

TargetInsulin-like growth factor 1 receptor(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM122837(US8735386, II-16)
Affinity DataIC50: 500nMpH: 7.4Assay Description:The kinase activity is measured by DELFIA assay (dissociation-enhanced lanthanide fluorescence immunoassay, Perkin Elmer). The cytoplasmic kinase dom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent