BDBM124200 US8748458, 4

SMILES ONC(=O)CCCCCCN(c1ccccn1)c1ccc2ccccc2n1

InChI Key InChIKey=JMWOJCWEYBYEOY-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 124200   

TargetHistone deacetylase 1(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50:  71nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50:  212nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50:  62nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 4(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50:  545nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50:  123nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 11(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50:  112nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 7(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50:  157nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50:  312nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 9(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50:  90nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50:  126nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Karus Therapeutics

US Patent
LigandPNGBDBM124200(US8748458, 4)
Affinity DataIC50:  16nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In DepthDetails US Patent