BDBM124889 US8759341, 16

SMILES Cc1[nH]nc2ccc(cc12)C1C2C(=O)OCC2=NC(=C1[N+]#[C-])C(F)(F)F

InChI Key InChIKey=GRKLXTVXJQFNOE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124889   

TargetHepatocyte growth factor receptor(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM124889(US8759341, 16)
Affinity DataIC50: 7nMpH: 7.5 T: 2°CAssay Description:For the assay, 50 mL of a 100-fold concentrated solution of the test compound in DMSO is pipetted into a black low-volume 384-well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent