BDBM12582 1-(4-chlorophenyl)-1H-1,2,3,4-tetrazole::1-(4-chlorophenyl)-1H-tetrazole::CHEMBL440394::US11634391, Compound 216::chlorophenyl-tetrazole compound 1

SMILES Clc1ccc(cc1)-n1cnnn1

InChI Key InChIKey=FVXFXVKZUVWQGE-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 12582   

TargetProthrombin(Homo sapiens (Human))
Astex

LigandPNGBDBM12582(1-(4-chlorophenyl)-1H-1,2,3,4-tetrazole | 1-(4-chl...)
Affinity DataIC50:  3.30E+5nMpH: 8.0 T: 2°CAssay Description:The cleavage of the substrate was followed by monitoring the change in fluorescence at 460 nm (excitation at 365 nm) for 25 min at room temperature o...More data for this Ligand-Target Pair
TargetPalmitoleoyl-protein carboxylesterase NOTUM(Homo sapiens (Human))
Ucl Business

US Patent
LigandPNGBDBM12582(1-(4-chlorophenyl)-1H-1,2,3,4-tetrazole | 1-(4-chl...)
Affinity DataIC50:  2.69E+4nMAssay Description:An Echo liquid handler was used to acoustically dispense 500 nL of compounds into dry Greiner 384-well plates (catalog #781076), followed by 25 μ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Astex

LigandPNGBDBM12582(1-(4-chlorophenyl)-1H-1,2,3,4-tetrazole | 1-(4-chl...)
Affinity DataIC50:  3.30E+5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Astex

LigandPNGBDBM12582(1-(4-chlorophenyl)-1H-1,2,3,4-tetrazole | 1-(4-chl...)
Affinity DataIC50:  3.30E+5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair