BDBM125923 US8772478, 15::US8772478, 8
SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)NC[C@H](N2CCCCC2)C(=O)NO)c2ccccc2n1
InChI Key InChIKey=XYPVMSYCSIAWKF-DEOSSOPVSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 125923
TargetDisintegrin and metalloproteinase domain-containing protein 33(Homo sapiens (Human))
Galderma Research & Development
US Patent
Galderma Research & Development
US Patent
Affinity DataIC50: 26nMpH: 7.4Assay Description:The products are solubilized in DMSO at a concentration of 10 mM. A serial 3-fold dilution over 10 points is carried out so as to have a concentratio...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 33(Homo sapiens (Human))
Galderma Research & Development
US Patent
Galderma Research & Development
US Patent
Affinity DataIC50: 112nMpH: 7.4Assay Description:The products are solubilized in DMSO at a concentration of 10 mM. A serial 3-fold dilution over 10 points is carried out so as to have a concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMpH: 7.4Assay Description:The products are solubilized in DMSO at a concentration of 10 mM. A serial 3-fold dilution over 10 points is carried out so as to have a concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 1.98E+3nMpH: 7.4Assay Description:The products are solubilized in DMSO at a concentration of 10 mM. A serial 3-fold dilution over 10 points is carried out so as to have a concentratio...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�
Curated by ChEMBL
Nestl�
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 7.4Assay Description:The products are solubilized in DMSO at a concentration of 10 mM. A serial 3-fold dilution over 10 points is carried out so as to have a concentratio...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 9(Homo sapiens (Human))
Galderma Research & Development
US Patent
Galderma Research & Development
US Patent
Affinity DataIC50: >1.00E+4nMpH: 7.4Assay Description:The products are solubilized in DMSO at a concentration of 10 mM. A serial 3-fold dilution over 10 points is carried out so as to have a concentratio...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Galderma Research & Development
US Patent
Galderma Research & Development
US Patent
Affinity DataIC50: >1.00E+4nMpH: 7.4Assay Description:The products are solubilized in DMSO at a concentration of 10 mM. A serial 3-fold dilution over 10 points is carried out so as to have a concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMpH: 7.4Assay Description:The products are solubilized in DMSO at a concentration of 10 mM. A serial 3-fold dilution over 10 points is carried out so as to have a concentratio...More data for this Ligand-Target Pair