BDBM125923 US8772478, 15::US8772478, 8

SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)NC[C@H](N2CCCCC2)C(=O)NO)c2ccccc2n1

InChI Key InChIKey=XYPVMSYCSIAWKF-DEOSSOPVSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 125923   

TargetDisintegrin and metalloproteinase domain-containing protein 33(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM125923(US8772478, 15 | US8772478, 8)
Affinity DataIC50:  26nMpH: 7.4Assay Description:The products are solubilized in DMSO at a concentration of 10 mM. A serial 3-fold dilution over 10 points is carried out so as to have a concentratio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 33(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM125923(US8772478, 15 | US8772478, 8)
Affinity DataIC50:  112nMpH: 7.4Assay Description:The products are solubilized in DMSO at a concentration of 10 mM. A serial 3-fold dilution over 10 points is carried out so as to have a concentratio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterstitial collagenase(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM125923(US8772478, 15 | US8772478, 8)
Affinity DataIC50:  3.00E+3nMpH: 7.4Assay Description:The products are solubilized in DMSO at a concentration of 10 mM. A serial 3-fold dilution over 10 points is carried out so as to have a concentratio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterstitial collagenase(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM125923(US8772478, 15 | US8772478, 8)
Affinity DataIC50:  1.98E+3nMpH: 7.4Assay Description:The products are solubilized in DMSO at a concentration of 10 mM. A serial 3-fold dilution over 10 points is carried out so as to have a concentratio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM125923(US8772478, 15 | US8772478, 8)
Affinity DataIC50:  210nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM125923(US8772478, 15 | US8772478, 8)
Affinity DataIC50: >1.00E+4nMpH: 7.4Assay Description:The products are solubilized in DMSO at a concentration of 10 mM. A serial 3-fold dilution over 10 points is carried out so as to have a concentratio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 9(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM125923(US8772478, 15 | US8772478, 8)
Affinity DataIC50: >1.00E+4nMpH: 7.4Assay Description:The products are solubilized in DMSO at a concentration of 10 mM. A serial 3-fold dilution over 10 points is carried out so as to have a concentratio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM125923(US8772478, 15 | US8772478, 8)
Affinity DataIC50: >1.00E+4nMpH: 7.4Assay Description:The products are solubilized in DMSO at a concentration of 10 mM. A serial 3-fold dilution over 10 points is carried out so as to have a concentratio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-1(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM125923(US8772478, 15 | US8772478, 8)
Affinity DataIC50:  4.50E+3nMpH: 7.4Assay Description:The products are solubilized in DMSO at a concentration of 10 mM. A serial 3-fold dilution over 10 points is carried out so as to have a concentratio...More data for this Ligand-Target Pair
In DepthDetails US Patent